HPE and partners launch Quantum Scaling Alliance to make quantum computing breakthroughs

John Martinis, 2025 Nobel Laureate, quantum computing specialist and co-founder and CTO at Qolab.

HPE and a consortium of seven other leading technology organizations have announced the formation of the Quantum Scaling Alliance, a global initiative dedicated to making quantum computing scalable, practical, and transformative across industries. Dr. Masoud Mohseni from HPE Labs, the applied research arm of HPE, oversees the initiative and serves as quantum system architect, coordinating efforts among eight organizations, each a leader in its field. The Alliance is co-led by John Martinis, 2025 Nobel Laureate recognized for pioneering advances in quantum computing and currently serving as co-founder and CTO at Qolab.

The consortium was formed to design and develop a practically useful and cost-effective quantum supercomputer, by leveraging the expertise of today’s supercomputing and semiconductor ecosystem. The Quantum Scaling Alliance brings together cross-functional expertise with the mission to scale quantum computing from proof-of-principle demonstrations to industry-scale applications. Founding members of the Quantum Scaling Alliance and their areas of expertise are:

1QBit: Fault-tolerant quantum error correction design and simulation, algorithm compilation, and automated resource estimations

Applied Materials, Inc.: Materials engineering and semiconductor fabrication

HPE: Full-stack quantum-HPC integration and software developments

Qolab: Qubit and circuit design

Quantum Machines: Hybrid quantum-classical control for scalable quantum computing

Riverlane: Quantum error correction

Synopsys: Simulation and analysis technology, EDA tools, and semiconductor IP

University of Wisconsin: Algorithms, benchmarks

“Quantum computers hold the key to transforming industries through their unique ability to tackle intrinsically quantum problems,” Martinis said. “By harnessing quantum systems, we can achieve breakthroughs in areas ranging from semiconductor manufacturing to sustainable fertilizer production – solving challenges previously thought insurmountable.”

“We are honored John Martinis is co-leading the Quantum Scaling Alliance with Masoud Mohseni,” said Alan Ho, Qolab CEO. “Qolab was founded on the principle that collaboration is key to accelerating commercially useful quantum computing.”

The Quantum Scaling Alliance is a global initiative working to make quantum computing scalable, practical, and impactful.

“We bring together leaders from industry, academia, startups, and national labs to drive progress in quantum by aligning quantum innovation with the existing semiconductor and HPC ecosystem, accelerating discovery by tackling problems that are uniquely suited to quantum computing, unlocking breakthroughs in areas like semiconductor optimization and quantum chemistry, and mobilizing shared resources to overcome barriers that no single group can solve alone

“Our goal is to ensure quantum becomes a truly viable, industry-wide computing paradigm – not a niche technology,” the Quantum Scaling Alliance stated. This includes exploring partnership opportunities, contributing expertise, or aligning on shared challenges in moving quantum computing forward.

From developer platforms to semiconductor manufacturing and simulation environments, our upcoming releases are designed with collaboration, openness, and scalability in mind,” the Aliance said. “Whether you’re a researcher, engineer, or organization working at the forefront of quantum computing, our tools are built to empower your work at every layer of the full stack.”

“In the span of four decades, quantum computation has evolved from an intellectual curiosity to a potentially realizable technology,” said Masoud Mohseni, lead author on a Quantum Computing integration study, which presents an HPC-QC full stack framework and its hybrid workload development capability with modular hardware/device-agnostic software integration approach. “Today, small-scale demonstrations have become possible for quantum algorithmic primitives on hundreds of physical qubits and proof-of-principle error-correction on a single logical qubit. Nevertheless, despite significant progress and excitement, the path toward a full-stack scalable technology is largely unknown. There are significant outstanding quantum hardware, fabrication, software architecture, and algorithmic challenges that are either unresolved or overlooked. These issues could seriously undermine the arrival of utility-scale quantum computers for the foreseeable future*. Furthermore, we argue that, to tackle industry-scale classical optimization and machine learning problems in a cost-effective manner, heterogeneous quantum-probabilistic computing with custom-designed accelerators should be considered as a complementary path toward scalability.”

HPE, a leader in high performance computing, is collaborating with the Quantum Scaling Alliance to build scalable, hybrid solutions that seamlessly integrate quantum capabilities with classical high-performance computing and advanced networking. This convergence is opening new frontiers in drug discovery, materials research, optimization, and secure data processing. The Alliance’s work not only accelerates scientific discovery and enterprise innovation today but also prepares organizations for the profound shifts ahead—from productivity gains through new acceleration technologies to the challenges of post-quantum security.

“For quantum to succeed as a viable long-term computing paradigm, it must scale by integrating with classical supercomputing systems,” said Mohseni, a distinguished technologist leading the quantum team at HPE. “The Quantum Scaling Alliance is offering a full-stack solution – a large partnership with horizontal integration that unlocks compute potential that is otherwise unachievable through a vertical approach.”